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homepage  RESEARCH  Latest Scientific Research
  • Publication in Soil Biology and Biochemistry by Prof.YU Mingjian's Laboratory, Institute of Ecology 2023-06-08 College of Life Sciences, Zhejiang University Title: Tree species richness increases spatial variation but not overall wood decompositionDonghao Wu, Sebastian Seibold, Katherina A. Pietsch, M.D. Farnon Ellwood, Mingjian YuAbstractEmpirical evidence for the positive relationship between tree species richness and wood decomposition is weak, despite the greater numbers of decomposers in diverse stands. Tree species identity affects decomposition...
  • Publication in Cell Research by Prof. WANG Yong's Laboratory, Institute of Biophysics 2023-06-01 College of Life Sciences, Zhejiang University Title: Structure and transport mechanism of the human calcium pump SPCA1Mengqi Wu, Cang Wu, Tiefeng Song, Kewu Pan, Yong Wang & Zhongmin LiuAbstractSecretory-pathway Ca2+-ATPases (SPCAs) play critical roles in maintaining Ca2+ homeostasis, but the exact mechanism of SPCAs-mediated Ca2+ transport remains unclear. Here, we determined six cryo-electron microscopy (cryo-EM) structures of huma...
  • Publication in Global Change Biology by Prof. CHENG Lei's Laboratory, Institute of Ecology 2023-05-26 College of Life Sciences, Zhejiang University Title: Coupled anaerobic methane oxidation and metal reduction in soil under elevated CO2Chenchao Xu, Naifang Zhang, Kaihang Zhang, Shuyao Li, Qing Xia, Jing Xiao, Maojun Liang, Weilei Lei, Junpan He, Gaiping Chen, Chengjun Ge, Xunhua Zheng, Jianguo Zhu, Shuijin Hu, Roger T. Koide, Mary K. Firestone, Lei ChengAbstractContinued current emissions of carbon dioxide (CO2) and methane (CH4) by hum...
  • Publication in The Journal of Clinical Investigation by Prof. YAN Qingfeng's Laboratory, Institute of Genetics and Regenerative Biology 2023-05-22 College of Life Sciences, Zhejiang University Title: 1-Deoxynojirimycin promotes cardiac function and rescues mitochondrial cristae in mitochondrial hypertrophic cardiomyopathyQianqian Zhuang, Fengfeng Guo, Lei Fu, Yufei Dong, Shaofang Xie, Xue Ding, Shuangyi Hu, Xuanhao D. Zhou, Yangwei Jiang, Hui Zhou, Yue Qiu, Zhaoying Lei, Mengyao Li, Huajian Cai, Mingjie Fan, ...
  • Publication in Nature by Prof. ZHOU Ruhong's Laboratory, Institute of Biophysics 2023-04-27 College of Life Sciences, Zhejiang University Title: Structural basis of BAM-mediated outer membrane β-barrel protein assemblyChongrong Shen, Shenghai Chang, Qinghua Luo, Kevin Chun Chan, Zhibo Zhang, Bingnan Luo, Teng Xie, Guangwen Lu, Xiaofeng Zhu, Xiawei Wei, Changjiang Dong, Ruhong Zhou, Xing Zhang, Xiaodi Tang & Haohao DongAbstractThe outer membrane structure is common in Gram-negative bacteria, mitochondria and chloroplasts, and co...
  • Publication in Nature Communications by Prof. LIN Aifu's Laboratory, Institute of Genetics and Regenerative Biology 2023-04-24 College of Life Sciences, Zhejiang University Title: LncRNA modulates Hippo-YAP signaling to reprogram iron metabolismXin-yu He, Xiao Fan, Lei Qu, Xiang Wang, Li Jiang, Ling-jie Sang, Cheng-yu Shi, Siyi Lin, Jie-cheng Yang, Zuo-zhen Yang, Kai Lei, Jun-hong Li, Huai-qiang Ju, Qingfeng Yan, Jian Liu, Fudi Wang, Jianzhong Shao, Yan Xiong, Wenqi Wang & Aifu LinAbstractIron metabolism dysregulation is tightly associated with cancer development...
  • Publication in Nature Communications by Prof. WANG Yong's Laboratory, Institute of Biophysics 2023-04-13 College of Life Sciences, Zhejiang University Title: Conformational cycle of human polyamine transporter ATP13A2Jianqiang Mu, Chenyang Xue, Lei Fu, Zongjun Yu, Minhan Nie, Mengqi Wu, Xinmeng Chen, Kun Liu, Ruiqian Bu, Ying Huang, Baisheng Yang, Jianming Han, Qianru Jiang, Kevin C. Chan, Ruhong Zhou, Huilin Li, Ancheng Huang, Yong Wang & Zhongmin LiuAbstractDysregulation of polyamine homeostasis strongly associates with human diseases...
  • Publication in PNAS by Prof. ZHOU Ruhong's Laboratory, Institute of Biophysics 2023-04-13 College of Life Sciences, Zhejiang University Title: A mutagenesis study of autoantigen optimization for potential T1D vaccine designYi Song, David R. Bell, Rizwan Ahmed, Kevin C. Chan, Sangyun Lee, Abdel Rahim A. Hamad, and Ruhong ZhouAbstractA previously reported autoreactive antigen, termed the X-idiotype, isolated from a unique cell population in Type 1 diabetes (T1D) patients, was found to stimulate their CD4+ T cells. This antigen was p...
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