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homepage  RESEARCH  Latest Scientific Research
  • Publication in Nucleic Acids Research by Prof. Chen Ming 's Laboratory, Institute of Bioinformatics 2026-05-12 College of Life Sciences, Zhejiang University Title:T2T-Hub: a central platform for analyzing plant and animal telomere-to-telomere genomesHaoyu chao, Zhonghao Ruan, Zhuojin Li, Xinkai Zhou, Shilong Zhang, Xingxing Shen, Cong Feng, Dijun Chen, Ming ChenAbstractT2T-Hub is a free, web-based platform designed to facilitate the analysis and visualization of telomere-to-telomere (T2T) genomes in plants and animals. The server integrates automated ...
  • Publication in Nature Communications by Prof. JianXiang Liu's Laboratory, Institute of Plant Biology 2026-05-12 College of Life Sciences, Zhejiang University Title: Signal peptide peptidase like proteases OsSPPL1 and OsSPPL2 facilitate ER-associated protein degradation in riceHai-Ping Lu, Jian-Hang Xu, Jia-Xin Chang, Hui-Dan Luo & Jian-Xiang LiuAbstractSignal peptide peptidases (SPPs) play a critical role in intramembrane proteolysis of signal peptides in mammals. However, their function in plants remains poorly understood. Here, we uncover the cri...
  • Publication in JOURNAL OF HEPATOLOGY by Prof. YANG Weijun's Laboratory, Institute of Cell 2026-05-11 College of Life Sciences, Zhejiang University Title: Setd4-expressing cells drive regenerative recovery in chronic liver injuryXi-Zheng Jia, Tian-Tian Zhuang, Ri-Sheng Yang, Yun-Wen Gu, Yi-Zhe Zeng, Christopher Wood, Jin-Shu Yang, Wei-Jun YangAbstractAs the metabolic center of the body, the liver is susceptible to chronic damage from toxic metabolites or exogenous substances, leading to the apoptosis of hepa...
  • Publication in Environmental Science & Technology by Prof. LU Zhenmei's Laboratory, Institute of Microbiology 2026-05-08 College of Life Sciences, Zhejiang University Title: Harnessing Microbial Bioremediation and Wastewater Valorization for Production of (Methyl)muconates via Engineered Metabolic Pathways in Aromatic Pollutant MixturesSiqing Fan, Xueni Fu, Xiaoyu Wang, Lvjing Wang, Hongyu Chen, Christopher E. French, Hongzhi Tang, Hao Ren*, Zhenmei Lu*AbstractIndustrial effluents, particularly (semi)coking wastewaters, pose significant environmental challenges...
  • Publication in The Plant Cell by Prof. James Whelan’s Laboratory, Institute of Botany 2026-04-30 College of Life Sciences, Zhejiang University Title: A four-dimensional spatial transcriptome atlas of barley caryopsis development and germination Marta Peirats-Llobet, Zorana Staka, Xiujuan Yang, Yanqiao Zhu, Cunman He, Bhavna Hurgobin, Felipe Ayora, Maria Sofia L Yangzon, Monika W Murcha, Valencia Marisa, Ghazanfar Abbas Khan, Runxuan Zhang, Iain Milne, Huixia Shou, Matthew R Tucker, Mathew G Lewsey, James Whelan*  Abst...
  • Publication in Nature Communications by Prof. CHEN Piaopiao's Laboratory, Institute of Ecology 2026-03-30 College of Life Sciences, Zhejiang University Title: Contrasting selective signatures of gene expression plasticity in response to antifungal clotrimazole and common environmental stresses in yeastYang Qian, Zhixuan Yao, Yu Yao, Ti Qin, Piaopiao Chen&Haoxuan LiuAbstractPhenotypic plasticity plays a key role in adaptation to fluctuating environments. However, its evolutionary significance remains debated, with conflicting views on whe...
  • Publication in Nucleic Acids Research by Prof. JIN Yongfeng’s Laboratory, Institute of Biochemistry 2026-03-24 College of Life Sciences, Zhejiang University Title: Regulatory paradigm of Dscam1 stochastic alternative splicing through conserved long-range RNA structuresHaiyang Dong, Bingbing Xu, Lili Wu, Zhechao Wang, Zedong Li, Jinpeng Xie, Jingsong Lv, Wanqing Yang, Nengcheng Bao, Huiru Qu, Jiayan Fu, Ru Yan, Yadong Wang, Lei Li, Feng Shi, Jianhua Huang, Xiaofeng Yang, Yongfeng Jin* AbstractPancrustacean Dscam1 genes encode 2 000–...
  • Publication in Cell Reports by Prof. LIN Aifu's Laboratory, Institute of Genetics and Regeneration 2026-03-12 College of Life Sciences, Zhejiang University Title: A CRISPR-based mitochondrial gene therapy tool derived by engineering guide RNAsYing Wang,Xinwan Su,Yu Chen, Yijian Chen, Chengyu Shi, Fangzhou Liu, Yuqi Ye, Panyi Sun, Manman Tan,Meng Yu,Ya Wang,Shanshan Xie,Jian Liu,Qingfeng Yan,Qiming Sun,Dante Neculai,Wei Liu, Jia...
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