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homepage  RESEARCH  Latest Scientific Research
  • Publication in Nature Communications by Prof. LIN Aifu’s Laboratory, Institute of Genetics and Regenerative Biology 2022-11-23 College of Life Sciences, Zhejiang University Title: Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylationChengyu Shi, Ying Wang, Minjie Wu, Yu Chen, Fangzhou Liu, Zheyuan Shen, Yiran Wang, Shaofang Xie, Yingying Shen, Lingjie Sang, Zhen Zhang, Zerui Gao, Luojia Yang, Lei Qu, Zuozhen Yang, Xinyu He, Yu Guo, Chenghao Pan, Jinxin Che, Huaiqiang Ju, Jian Liu, Zhijian Cai, Qingfeng Yan, Luyang Yu,...
  • Publication in Nature by Prof. CHEN Caiyong's Laboratory, Institute of Cell and Developmental Biology 2022-10-21 College of Life Sciences, Zhejiang University Title: HRG-9 homologues regulate haem trafficking from haem-enriched compartmentsFengxiu Sun, Zhenzhen Zhao, Mathilda M. Willoughby, Shuaiqi Shen, Yu Zhou, Yiyan Shao, Jing Kang, Yongtian Chen, Mengying Chen, Xiaojing Yuan, Iqbal Hamza, Amit R. Reddi & Caiyong ChenAbstractHaem is an iron-containing tetrapyrrole that is critical for a variety of cellular and physiological processes. Haem bindin...
  • Publication in Blood by Prof. CHEN Caiyong's Laboratory, Institute of Cell and Developmental Biology 2022-09-09 College of Life Sciences, Zhejiang University Title: Grab regulates transferrin receptor recycling and iron uptake in developing erythroblastsMengying Chen, Yuhan Zhang, Kailun Jiang, Weixi Wang, He Feng, Ru Zhen, Chingyee Moo, Zhuonan Zhang, Jiahai Shi, Caiyong ChenAbstractDeveloping erythroblasts acquire massive amounts of iron through the transferrin (Tf) cycle, which involves endocytosis, sorting, and recycling of the Tf-Tf receptor (Tfrc...
  • Publication in New Phytologist by Prof. LIU Jianxiang's Laboratory, Institute of Plant Biology 2022-08-31 College of Life Sciences, Zhejiang University Title: A competition-attenuation mechanism modulates thermoresponsive growth at warm temperatures in plantsWei Li, Ying-Ying Tian, Jin-Yu Li, Li Yuan, Lin-Lin Zhang, Zhi-Ye Wang, Xiaodong Xu, Seth Jon Davis, Jian-Xiang LiuFirst published: 26 August 2022https://doi.org/10.1111/nph.18442Summary•     Global warming has profound impact on growth and development, and plants con...
  • Publication in Nature Metabolism by Prof. LIN Aifu's Laboratory, Institute of Genetics and Regenerative Biology 2022-08-24 College of Life Sciences, Zhejiang University Title: Long non-coding RNA SNHG6 couples cholesterol sensing with mTORC1 activation in hepatocellular carcinomaFangzhou Liu, Tian Tian, Zhen Zhang, Shanshan Xie, Jiecheng Yang, Linyu Zhu, Wen Wang, Chengyu Shi, Lingjie Sang, Kaiqiang Guo, Zuozhen Yang, Lei Qu, Xiangrui Liu, Jian Liu, Qingfeng Yan, Huai-qiang Ju, Wenqi Wang, Hai-long Piao, Jianzhong Shao, Tianhua Zhou & Aifu LinAbstractCho...
  • Publication in Global Change Biology by Prof. HUANG Jianguo's Laboratory, Institute of Ecology 2022-08-22 College of Life Sciences, Zhejiang University Title: Climate warming leads to advanced fruit development period of temperate woody species but divergent changes in its lengthQianqian Ma, Heikki Hänninen, Frank Berninger, Xiaobo Li, Jian-Guo HuangFirst published: 28 July 2022https://doi.org/10.1111/gcb.16357AbstractClimate warming has significantly altered the phenology of plants in recent decades. However, in contrast to the widely reported w...
  • Publication in Plant, Cell & Environment by Prof. SHOU Huixia's Laboratory, Institute of Plant Biology 2022-08-10 College of Life Sciences, Zhejiang University Title: Functional characterization of the three Oryza sativa SPX-MFS proteins in maintaining phosphate homoeostasisRunze Guo, Qi Zhang, Yinghui Ying, Wenying Liao, Yu Liu, James Whelan, Mao Chuanzao, Huixia ShouFirst published: 31 July 2022https://doi.org/10.1111/pce.14414AbstractPlant vacuoles serve as the primary intracellular compartments for phosphorus (P) storage. The Oryza sativa g...
  • Publication in Nature Chemical Biology by Prof. ZHOU Ruhong's Laboratory & YI Wen's Laboratory 2022-07-27 College of Life Sciences, Zhejiang University Title: O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1Qiang Zhu, Hong Zhou, Liming Wu, Zhenyuan Lai, Didi Geng, Weiwei Yang, Jie Zhang, Zhiya Fan, Weijie Qin, Yong Wang, Ruhong Zhou & Wen YiPublished: 25 July 2022AbstractOncogenic Kras-activated pancreatic ductal adenocarcinoma (PDAC) cells highly rely on an unconventional glutamine catabolic pathway ...
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