Publication in Nature Communications by Prof. CHEN Ming's Laboratory, Institute of Biophysics
.29, 2025
College of Life Sciences, Zhejiang University
Title: GraphVelo allows for accurate inference of multimodal velocities and molecular mechanisms for single cellsYuhao Chen, Yan Zhang, Jiaqi Gan, Ke Ni, Ming Chen, Ivet Bahar & Jianhua Xing AbstractRNA velocities and generalizations emerge as powerful approaches for extracting time-resolved information from high-throughput snapshot single-cell data...
Publication in Trends in Pharmacological Sciences by Prof. YI Wen and Researcher ZHU Qiang's Laboratory, Institute of Biochemistry
.21, 2025
College of Life Sciences, Zhejiang University
Title: Targeting glycosylation to enhance tumor immunotherapyQiang Zhu, Xiaoming Chen, Xiaotao Duan, Jianwei Sun, Wen YiAbstractGlycans are complex sugar modifications found on cell surfaces that play crucial roles in biological processes. Glycosylation patterns are aberrantly altered in the tumor microenvironment (TME), which helps cancer cells escape immune surveillance by creating a tumor-...
Publication in Advanced Science by Prof. LIN Aifu's Laboratory, Institute of Genetics and Regenerative Biology
.20, 2025
College of Life Sciences, Zhejiang University
Title: PD-L1-Targeting Biomimetic Photoresponsive Thermosensitive Liposomes for Triple-Negative Breast CancerManman Tan, Chengyu Shi, Guangyi Chi, Xinwan Su, Fangzhou Liu, Linyu Zhu, Guangqian Cheng, Xiangyi Chen, Meng Yu, Yijian Chen, Ying Wang, Yu Chen, ShuLing Yan, Wenfei Wu, Qingfeng Yan, Jianzhong Shao, Kai W...
Publication in ACS Nano by Prof. ZHOU Ruhong's Laboratory, Institute of Biophysics
.01, 2025
College of Life Sciences, Zhejiang University
Title: Overcoming Radiotherapy Resistance in Chordoma through the Synergistic Action of Selenium-Containing Nanoparticles and THZ1Lianxue Zhang, Yun Teng, Hai Yang, Jianxiang Huang, Zhaoqi Shi, Cenhao Wu, Zaixing Yang, Liquan Huang, Jun Zou, Ruhong ZhouAbstractChordoma presents a formidable therapeutic challenge due to its distinct anatomical location, thus complicating its complete surgical resec...
Publication in Nature Communications by Prof. WANG Zhiye's Laboratory, Institute of Botany
.30, 2025
College of Life Sciences, Zhejiang University
Title: N6-methyladenosine modifications stabilize phosphate starvation response–related mRNAs in plant adaptation to nutrient-deficient stressKai Liu, Xiaojia Wang, Jingyi Wang, Shuman Wang, Haiyan Bai, Weiguo Dong, Lulu Qiao, Qiongli Jin, Zhonghui Zhang, Guan-Zheng Luo, Zhiye WangAbstractPhosphorus (P) is an essential macronutrient for plant growth. However, the availability of inorgani...
Publication in PNAS by Prof. HUANG Jianguo's Laboratory, Institute of Ecology
.29, 2025
College of Life Sciences, Zhejiang University
Title: Soil nitrogen drives inverse acclimation of xylem growth cessation to rising temperature in Northern Hemisphere conifers Yaling Zhang, Jian-Guo Huang, Minhuang Wang, Wenjin Wang, Feiyu Yang, Annie Deslauriers, Patrick Fonti, Eryuan Liang, Harri Mäkinen, Walter Oberhuber, et al.Abstract Controlled experiments suggest that the seasonal build-up of nitrogen (N) limitation ...
Publication in Briefings in Bioinformatics by Prof. ZHOU Ruhong's Laboratory, Institute of Biophysics
.29, 2025
College of Life Sciences, Zhejiang University
Title: A free energy perturbation-assisted machine learning strategy for mimotope screening in neoantigen-based vaccine design Qinglu Zhong, Kevin C Chan, Lei Fu, Ruhong Zhou AbstractNeoantigen-based immunotherapy has emerged as a promising approach for cancer treatment. One key strategy in neoantigen-based vaccine design is to alter known neoantigens into enhanced mimotopes that el...
Publication in Journal of Ecology by Prof. YU Mingjian 's Laboratory, Institute of Ecology
.25, 2025
College of Life Sciences, Zhejiang University
Title: Insect herbivores and soil fertility drive variation in density-dependent seedling dynamics across a fragmented landscapeYanping Lei, Robert Bagchi, Jinliang Liu, Zhonghan Wang, Jirui Wang, Guang Hu, Mingjian Yu*AbstractHabitat fragmentation is associated with decreased species diversity. However, the effects of fragmentation on the processes that maintain diversity, such as enemy...
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