ZJU scientists identify O-GlcNAcylation as cause of pancreatic tumor growth by regulating MDH1
.19, 2022
College of Life Sciences, Zhejiang University
Publication in Plant, Cell & Environment by Prof. SHOU Huixia's Laboratory, Institute of Plant Biology
.10, 2022
College of Life Sciences, Zhejiang University
Title: Functional characterization of the three Oryza sativa SPX-MFS proteins in maintaining phosphate homoeostasisRunze Guo, Qi Zhang, Yinghui Ying, Wenying Liao, Yu Liu, James Whelan, Mao Chuanzao, Huixia ShouFirst published: 31 July 2022https://doi.org/10.1111/pce.14414AbstractPlant vacuoles serve as the primary intracellular compartments for phosphorus (P) storage. The Oryza sativa g...
Publication in Nature Chemical Biology by Prof. ZHOU Ruhong's Laboratory & YI Wen's Laboratory
.27, 2022
College of Life Sciences, Zhejiang University
Title: O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1Qiang Zhu, Hong Zhou, Liming Wu, Zhenyuan Lai, Didi Geng, Weiwei Yang, Jie Zhang, Zhiya Fan, Weijie Qin, Yong Wang, Ruhong Zhou & Wen YiPublished: 25 July 2022AbstractOncogenic Kras-activated pancreatic ductal adenocarcinoma (PDAC) cells highly rely on an unconventional glutamine catabolic pathway ...
ZJU scientists unravel how SUMOylation coordinates endothelial angiogenic signaling
.18, 2022
College of Life Sciences, Zhejiang University
Publication in Structure by Prof. ZHAO Ye & HUA Yuejin's Laboratory, Institute of Biophysics
.18, 2022
College of Life Sciences, Zhejiang University
Title: Mechanisms of helicase activated DNA end resection in bacteriaYing Xu, Lingyi Xu, Chen Qin, Liangyan Wang, Jiangtao Guo, Yuejin Hua, Ye ZhaoPublished: July 15, 2022DOI: https://doi.org/10.1016/j.str.2022.06.005SummaryDNA end resection mediated by the coordinated action of nuclease and helicase is a crucial step in initiating homologous recombination. The end-resection apparatus NurA nucleas...
Publication in Science Advances by Prof. JIN Yongfeng's Laboratory, Institute of Biochemistry
.08, 2022
College of Life Sciences, Zhejiang University
Title: Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificitySHOUQING HOU, GUO LI, BINGBING XU, HAIYANG DONG, SHIXIN ZHANG, YING FU, JILONG SHI, LEI LI, JIAYAN FU, FENG SHI, YIJUN MENG AND YONGFENG JINAbstractThe Down syndrome cell adhesion molecule 1 (Dscam1) gene can generate tens of thousands of isoforms via alternative spl...
Publication in PNAS by Prof. YU Luyang & QIU Cong's Laboratory, Institute of Genetics and Regenerative Biology
.27, 2022
College of Life Sciences, Zhejiang University
Title: FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesisXiaolong Zhu, Cong Qiu, Yiran Wang, Yuanqing Jiang, Yefeng Chen, Linge Fan, Ruizhe Ren, Yunyun Wang, Yu Chen, Yanzhi Feng, Xiaofei Zhou, Yunhui Zhu, Zhen Ge, Dongwu Lai, Lingfeng Qin, Michael Simons, and Luyang YuAbstractAngiogenesis contributes fundamentally to embryonic development, tissue homeostasis, and wound...
Publication in Science China Life Sciences by Prof. JIN Yongfeng's Laboratory, Institute of Biochemistry
.22, 2022
College of Life Sciences, Zhejiang University
Title: Recent advances in RNA structuromeBingbing Xu, Yanda Zhu, Changchang Cao, Hao Chen, Qiongli Jin, Guangnan Li, Junfeng Ma, Siwy Ling Yang, Jieyu Zhao, Jianghui Zhu, Yiliang Ding, Xianyang Fang, Yongfeng Jin, Chun Kit Kwok, Aiming Ren, Yue Wan, Zhiye Wang, Yuanchao Xue, Huakun Zhang, Qiangfeng Cliff Zhang & Yu ZhouAbstractRNA structures are essential to support RNA functions and regulatio...
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